Conclusion Telomere reduction and telomerase activation are critical factor during oncogenesis.
結(jié)論端??s短并激活端粒酶是涎腺腫瘤形成的重要因素.
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Telomerase system is the genetic name of telomerase and telomere.
端粒酶系統(tǒng)是端粒和端粒酶的總稱.
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Telomere locates on the terminal of DNA containing repeat DNA sequence.
端粒是位于染色體末端的串聯(lián)重復核苷酸序列.
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ALT and TA mechanisms are dominant maintenance mechanisms of the telomere length.
端粒長度的維持機制主要有ALT機制和TA機制.
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Considering the risks of telomere - extension therapy, he thinks that scientists have bigger fish to fry.
因為延長端粒療法具有危險, 他認為還有更大的問題需要科學家去解決.
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We summarize the present research of telomerase and telomere and their applications on ocular disease.
在此,我們就端粒、端粒酶研究現(xiàn)狀及其與眼科疾病的關(guān)系和應用進展作一綜述.
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Objective To evaluate the role of telomere and DCC in tumor transformation and progression.
目的 分析端粒長度及DCC基因 mRNA 表達在大腸癌及腺瘤發(fā)生發(fā)展中的作用.
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The telomere is like a cellular clock, because every time a cell divides, the telomere shortens.
端粒就像是細胞的時鐘, 因為在每次細胞分裂時它都首先要縮短.
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Therefore, TRF 2 may protect chromosome ends by maintaining the correct structure at telomere termini.
因此, TRF2可保護染色體末端保持正確的結(jié)構(gòu),端粒末端.
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Can telomere maintenance be eliminated effectively ( and selectively ) enough by more tractable approaches?
端粒維持可以由足夠有效地 ( 或選擇性地 ) 更易控制的途徑而有效地被排除 嗎 ?
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Researchers estimate that telomere maintenance activity occurs in about 90 % of human cancers.
研究人員估計,90%的癌癥中端粒一直處于活躍狀態(tài).
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Overall, the study participants had an average telomere loss of 21 nucleotides ( structural units ) per year.
總的來說, 該項研究的參與者每年平均損失21個核甘酸 ( 結(jié)構(gòu)單位 ).
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Telomere is at the end of the chromosome in eukaryotic cells and protects chromosomes.
摘要端粒位于真核細胞染色體末端,起保護染色體末端的作用.
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"telomeres act as caps to keep the sticky ends of chromosomes from randomly clumping together"